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Biosynthesized nanoparticles of Tibetan medicine mercuric sulfide preparation to promote endocytosis and realize drug crossing through blood brain barrier

β-HgS as the main component of Tibetan medicine Zuotai (ZT) is widely used in the treatment of central nervous system diseases. Although the synergism of HgS has been clinically verified for more than 2000 years, its...

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A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods

In this study, chronic restraint stressmouse models were used to simulate chronic stress, and behavioral tests were conducted, including the open field test, tail suspension testand forced swimming test.

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A Study of Sex Differences in the Biological Pathways of Stress Regulation in Mice

Stress is closely related to life, and it can also cause many mental disorders. However, there are significant sex differences in neuropsychiatric disorders associated with stress, particularly in depression, where th...

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Gut microbiome and diet contribute to ecological niche differentiation between argali (Ovis ammon hodgsoni) and blue sheep (Pseudois nayaur) on the Qinghai-Tibet Plateau

The gut microbiota plays a critical role in plant digestion, nutrient absorption, and ecological adaptation in herbivores.

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Comparative macrogenomics reveal plateau adaptation of gut microbiome in cervids

BackgroundDiverse gut microbiota in animals significantly influences host physiology, ecological adaptation, and evolution.

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