Research News

Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression

We analyzed the chromatin accessibility of undifferentiated spermatogonia at the single-cell level and identified 37 positive TF regulators that may have potential roles in dictating SSC fates. The transcription facto...

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Taxon-specific, phased siRNAs underlie a speciation locus in monkeyflowers

Taxon-specific small RNA loci are widespread in eukaryotic genomes, yet their role in lineage-specificadaptation, phenotypic diversification, and speciation is poorly understood. Here, we report that aspeciation locus...

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A homotetrameric hemoglobin expressed in alveolar epithelial cell increases blood oxygenation in high-altitude plateau pika (Ochotona curzoniae)

The plateau pika ( Ochotona curzoniae ) is native to the Qinghai-Tibet Plateau . In this study , the gene that encodes a heme-binding protein in the pulmonary surfactant ( PS ) of the pika is identified .Therefore , s...

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Grazing pressure index considering both wildlife and livestock in Three-River Headwaters, Qinghai-Tibetan Plateau

Grassland is not only the natural habitats for the survival of wild animals, but also the material guarantees for livestock husbandry. However, the previous studies on grassland carrying capacity are mostly only consi...

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Long read genome assemblies complemented by single cell RNA-sequencing reveal genetic and cellular mechanisms underlying the adaptive evolution of yak

Yak is one of the largest ruminants living in the areas with the highest average altitude in the world and physiologically adapted to hypoxic and cold environment. The domestic yak normally lives between 3000 and 5000...

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