Transcription factor E4F1 dictates spermatogonial stem cell fate decisions by regulating mitochondrial functions and cell cycle progression

September 26, 2023We analyzed the chromatin accessibility of undifferentiated spermatogonia at the single-cell level and identified 37 positive TF regulators that may have potential roles in dictating SSC fates. The transcription factor E4F1 is expressed in spermatogonia, an...
Taxon-specific, phased siRNAs underlie a speciation locus in monkeyflowers

February 10, 2023Taxon-specific small RNA loci are widespread in eukaryotic genomes, yet their role in lineage-specificadaptation, phenotypic diversification, and speciation is poorly understood. Here, we report that aspeciation locus in monkeyflowers (Mimulus)