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Identification of Candidate Genes Related to Hybrid Sterility by Genomic Structural Variation and Transcriptome Analyses in Cattle-yak

Notably, we discovered that the expression of X chromosome-linkedgenes was upregulated in the testis of cattle-yak compared with yak, suggesting a possible abnormality in the process of meiotic sex chromosome inactiva...

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Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro

Developmental competence of oocytes matured in vitro is limited due to a lack of complete understanding of metabolism and metabolic gene expression during oocyte maturation and embryo development.

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Rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment optimization, UPLC-QTOF-MS/MS, molecular docking and in vitro validation

In the present study, an efficient strategy has been established for rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment opti...

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Multi-omics reveal the gut microbiota-mediated severe foraging environment adaption of small wild ruminants in the Three-River-Source National Park, China

The Tibetan antelope, blue sheep, and Tibetan sheepare the dominant small ruminants in the Three-River-Source National Park.

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Spatiotemporal overlap among snow leopard, bharal, and free-ranging livestock: Suggestions on mitigating human-snow leopard conflict

Predation on livestock by large carnivores, such as snow leopard, is a global issue that leads to human-wildlife conflicts.

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