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A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii)

Tibetan antelope, a wild ruminant endemic to the Qinghai-Tibetan Plateauin China, has evolved a series of genetic and physiological adaptation strategies to thrive in the harsh plateau environments.

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Soil microbial network complexity predicts soil multifunctionality better than soil microbial diversity during grassland-farmland-shrubland conversion on the Qinghai-Tibetan Plateau

In this study, we evaluated the effects of land-use changes from alpine grassland to farmland to shrubland on soil factors and soil microbial characteristics and investigated the associations between aboveground bioma...

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Identification of Candidate Genes Related to Hybrid Sterility by Genomic Structural Variation and Transcriptome Analyses in Cattle-yak

Notably, we discovered that the expression of X chromosome-linkedgenes was upregulated in the testis of cattle-yak compared with yak, suggesting a possible abnormality in the process of meiotic sex chromosome inactiva...

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Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro

Developmental competence of oocytes matured in vitro is limited due to a lack of complete understanding of metabolism and metabolic gene expression during oocyte maturation and embryo development.

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Rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment optimization, UPLC-QTOF-MS/MS, molecular docking and in vitro validation

In the present study, an efficient strategy has been established for rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment opti...

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