Integrated ultrasensitive metabolomics and single-cell transcriptomics identify crucial regulators of sheep oocyte maturation and early embryo development in vitro
September 05, 2024 Developmental competence of oocytes matured in vitro is limited due to a lack of complete understanding of metabolism and metabolic gene expression during oocyte maturation and embryo development.
Rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment optimization, UPLC-QTOF-MS/MS, molecular docking and in vitro validation
August 15, 2024 In the present study, an efficient strategy has been established for rapid screening of potential α-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment opti...
Multi-omics reveal the gut microbiota-mediated severe foraging environment adaption of small wild ruminants in the Three-River-Source National Park, China
July 25, 2024 The Tibetan antelope, blue sheep, and Tibetan sheepare the dominant small ruminants in the Three-River-Source National Park.
Spatiotemporal overlap among snow leopard, bharal, and free-ranging livestock: Suggestions on mitigating human-snow leopard conflict
June 13, 2024 Predation on livestock by large carnivores, such as snow leopard, is a global issue that leads to human-wildlife conflicts.
Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility" target="_blank">Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility
May 10, 2024 Leydig cells are essential components of testicular interstitial tissue and serve as a primary source of androgen in males.